Nutrition And Wound Healing
Write short note on complications of wounds.
Answer.
Following are the complications of wounds:
“Factors influencing success with nutrition and wound healing knowledge: Q&A”
- Infection: Itis the most important complication which is responsible for delay in wound healing.
- Bacteria mainly remain endogenous.
- Based onpus culture and blood report antibiotics should be prescribed.
- Scar: Present due to infection.
- Hypertrophic scar and Keloid formation due to altered collagen synthesis in wound healing process.
- Skin pigmentation
- Marjolin ulcer: As repeated breakdown of hypertrophic scar occur it becomes Marjolin’s ulcer.
“Understanding nutrition and wound healing through FAQs: Key nutrients explained”
Question.12. Write short note on general factors affecting wound healing.
Answer.
General Factors Of Affecting Wound Healing.
General factors affecting wound healing are as follows:
- Age
- Malnutrition
- Vitamin defiiency (Vitamin C, Vitamin A)
- Anemia
- Malignancy
- Uremia
“Steps to explain nutrition and wound healing: Causes vs symptoms vs treatment: Q&A guide”
- Jaundice
- Diabetes, metabolic diseases
- HIV and immunosuppressive diseases
- Steroids and cytotoxic drugs
“Importance of studying nutrition for optimal wound healing: Questions explained”
- Age: In younger age group, wound healing is faster and bettr while in elderly healing is delayed due to reduction in collagen synthesis, epithelialization, growth factors and angiogenesis. But facial scar will be excellent in old individuals.
- Malnutrition and vitamin deficiency: Adequate vitamin, trace elements, fatt acids, and proteins are essential for wound healing. Vitamin A deficiency affects monocyte activation, inflammatory phase, collagen synthesis and growth factor actions.
- Vitamin K deficiency affects synthesis of prothrombin (ll), factors VII, IX and X. vitamin E, being an antioxidant stabilizes the cell membrane. Vitamin C deficiency impairs collagen synthesis, firoblast proliferation and angiogenesis; increases the capillary fragility and susceptibility for infection. Zinc is an essential cofactor for RNA and DNA polymerase;magnesium is a co-factor for synthesis of proteins and collagen; copper is a required co-factor for cytochrome oxidase.
- Anemia: Hemoglobin less than 8% causes poor oxygenation of tissues preventing healing of the wounds.
- Diabetes mellitus: In diabetic patients, wound healing is delayed because of several factors such as microangiopathy, atherosclerosis, decreased phagocytic activity, proliferation of bacteria due to high blood sugar etc.
- Metabolic causes: Obesity causes hypoperfusion, reduced microcirculation, increased wound tension, and hence prevents wound healing.
- Jaundice and uremia: Jaundiced and uraemic patients have poor wound healing because firoblastic repair is delayed.
- HIV and immunosuppressive diseases and malignancy: HIV and immunosuppression of varying causes, malignancy leads into poor wound healing.
- Drugs: Steroids interfere with activation of macrophages, fibroblasts, and angiogenesis in the early phase of healing (proliferative).
“Common challenges in addressing malnutrition in wound healing effectively: FAQs provided”
Nonsteroidal anti-inflammatory drugs (NSAIDs) decrease collagen production. Chemotherapeutic agents used in oncology inhibit cellular proliferation, protein synthesis. Alcohol consumption decreases the phagocyte response and pro-inflammatory cytokine release; diminishes host response and thus increasing the infection rate.
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